Certified Emergency Nurse (CEN) Practice Test 2025 - Free CEN Practice Questions and Study Guide

The neurological signs associated with serotonin syndrome primarily involve heightened activity in the central nervous system, which manifests as hyperreflexia and anxiety.

Hyperreflexia refers to overactive or exaggerated reflexes, which is a common symptom seen in serotonin syndrome due to increased serotonergic activity within the nervous system. This can also include other reflex abnormalities, such as clonus (rapid, rhythmic contractions of the muscles) and tremors. These symptoms arise from the overstimulation of serotonin receptors, particularly in the central nervous system.

Anxiety is also prevalent in patients experiencing serotonin syndrome, contributing to an altered mental state. This symptom can escalate to more severe manifestations, including agitation and confusion, but anxiety often presents as an initial warning sign.

Understanding these symptoms is essential for recognizing serotonin syndrome quickly, as it can lead to more severe complications if not addressed. The combination of hyperreflexia and anxiety serves as an important flag that indicates the presence of altered serotonergic function in the brain.